منابع مشابه
Tumour phospholipid metabolism.
Following the impetus of early clinical and experimental investigations, in vivo and in vitro MRS studies of tumours pointed in the eighties to the possible significance of signals arising from phospholipid (PL) precursors and catabolites as novel biochemical indicators of in vivo tumour progression and response to therapy. In the present decade, MRS analyses of individual components contributi...
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Using Ehrlich ascites tumour cells, the short-term effects of the therapeutic glucocorticoid Methylprednisolone (MP) on the cellular energy metabolism were studied. ATP-consuming processes involved in the rapid MP effects were identified indirectly from the effects of MP on cellular oxygen consumption related to the inhibition of respiration by selective inhibitors of Ca(2+)-ATPase and protein ...
متن کاملControl of Energy Exchange
The intention of the authors of the present monograph in the field of thermal physiology has been to present briefly an analytic and authoritative treatment of the significant highlights that concern the exchange of energy between man and his thermal environment. The book is written for medical and graduate students as well as biophysicists and biomedical engineers. The text is consolidated int...
متن کاملKetone-body metabolism in tumour-bearing rats.
During starvation for 72 h, tumour-bearing rats showed accelerated ketonaemia and marked ketonuria. Total blood [ketone bodies] were 8.53 mM and 3.34 mM in tumour-bearing and control (non-tumour-bearing) rats respectively (P less than 0.001). The [3-hydroxybutyrate]/[acetoacetate] ratio was 1.3 in the tumour-bearing rats, compared with 3.2 in the controls at 72 h (P less than 0.001). Blood [glu...
متن کاملAmino acid metabolism in tumour-bearing mice.
Mice bearing the Lewis lung carcinoma showed a high tumour glutaminase activity and significantly higher concentrations of most amino acids than in both the liver and the skeletal muscle of the host. Tumour tissue slices showed a marked preference for glutamine, especially for oxidation of its skeleton to CO2. It is proposed that the metabolism of this particular carcinoma is focused on amino a...
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ژورنال
عنوان ژورنال: Nature Reviews Cancer
سال: 2006
ISSN: 1474-175X,1474-1768
DOI: 10.1038/nrc1955